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Anti-Wrinkle Injection


What is the Anti-Wrinkle Injection?

The anti-wrinkle injection originates from the bacterium Clostridium botulinum, as this bacterium produces a toxin during the sporulation process that blocks communication between the nerves, leaving the skin tougher and more resistant. It is therefore often used in cosmetic treatments. However, the receptors that are blocked by the toxin are continually replaced, so its effect is not permanent (lasting up to 4-5 months).

In our clinic we use the anti-wrinkle injection to reduce wrinkles and expression lines in the eye area (such as crow's feet), in the forehead area, or in the space between the eyebrows (glabella).

The effect of the application of the toxin promotes the smoothing of wrinkles and expression lines on the face. These expression lines can be caused by several factors, including the contraction of facial muscles during the years, a bad diet, facial aging, tobacco, excessive sun exposure, among others.

Performance of anti-wrinkle injection treatment

As the toxin acts on the expression wrinkles (by relaxing the muscles of the face), this procedure allows the results obtained to be more visible and faster than when using anti-aging creams, even though these exist.

There is not exactly a base age for using this treatment. However, it is generally indicated for adults who have expression lines (more or less advanced), or wish to prevent the signs of aging on the skin. In other words, the use of the toxin can vary depending on the age at which:

  • at younger ages it serves to prevent the formation or deepening of expression lines;
  • At other ages it serves as an expression wrinkle attenuator.

The treatment step by step

  1. Evaluation
    Schedule your evaluation appointment.
  2. First consultation - clinical
    During your consultation, you will have the opportunity to discuss your treatment and the results you want to achieve with our medical specialist.
  3. Treatment
    Treatment begins with cleaning and disinfecting the skin. Then, small doses are applied through a syringe with a very thin needle, generating no pain or discomfort. These applications are made with a space of 1.5 cm between the treated areas. The number of applications needed and the points where they will be applied are defined according to the initial objectives. Each treatment session lasts approximately 30 minutes. Maintenance is recommended between 4 to 6 months.
  4. Post-treatment / results
    The final result of the treatment is not immediate, but with only 1 session it is already possible to see some results. However, these can be visibly seen between 2 and 5 days after the session, and only two weeks after the treatment reaches its apex, eliminating wrinkles, expression lines, and reflecting a younger-looking skin.
    If retouching is necessary, it should be done between 10 and 21 days.

Note: side effects can last an average of 48 hours. Find out more in the FAQ section below.

Anti-Wrinkle Injection | facial harmonization

Which areas can be treated?

The toxin is generally used to treat expression marks on the upper third of the face, particularly for:

  • eliminate crow's feet;
  • attenuate wrinkles that form between the eyebrows; and
  • attenuate the horizontal lines on the forehead.

The procedure relaxes the muscles in order to disguise the appearance of existing wrinkles and prevent the appearance of deeper ones.

It is, however, possible to apply Botox to other regions of the face, as follows:

  • on the ends of the eyebrows in order to make them more arched;
  • on the chin, to reduce wrinkles that appear there;
  • on the neck and neck, to eliminate vertical creases that usually appear;
  • it is also possible to correct the gummy smile.


  • 1 zone: 250
  • 2 zones: 300
  • 3 zones: 350
  • Sorriso Gengival: desde 320€
  • Masseter/Bruxism: 390
  • Mento: 150

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Frequently Asked Questions

How long do the results last?

The duration of the results is, on average, about 4 to 6 months. However, the lifestyle of the person also has an impact on the durability of this procedure, as well as the care they take with their skin on a daily basis.

Para mais informações, consulte nosso artigo, que serve como um guia completo sobre a aplicação de toxina.

Is any care needed before the procedure?

Some cosmetic products are contraindicated before and after the procedure. This is also the case with some aesthetic treatments. During the first evaluation appointment, your health and skin care history will be taken into account to understand if there are any contraindications.

What is the post-procedure care?

After treatment, the skin may become inflamed and sensitive around the injection site, improving in 24-48 hours. Rarely, allergic reactions to the product, such as redness and itching, may occur, which can be treated with topical anti-inflammatory drugs or oral tablets, as directed by your doctor.

It is a procedure that does not require much time for recovery. However, it is recommended to use sunscreen and avoid excessive exposure to the sun, as well as to avoid intense physical activities during the recovery period (day of the procedure). The day after the procedure, normal activities can be resumed, requiring no more rest.

What are the contraindications?

The procedure is contraindicated for patients who are allergic to the components in the anti-wrinkle injection formula, pregnant and lactating women, and people with neuromuscular diseases.

What are the complementary treatments?

There are other treatments that can be complementary to this one, including the following:

Anti-wrinkle creams

Anti-wrinkle creams fight aging and moisturize the skin. They are divided into cosmetics, dermocosmetics, and nutricosmetics.

  • cosmetics have superficial action and act to moisturize and protect the skin from the action of wind, heat, and pollution;
  • The dermocosmetics act in a deeper way, they have actives and substances that are more potent in combating spots, scars, and flabbiness;
  • nutricosmetics, such as collagen and antioxidants, help improve the skin from the inside out.

No Needle Dermal Filler

Dermal Filler is a technique that consists in injecting hyaluronic acid to fill wrinkles, furrows, depressions. It also serves for remodeling, such as zygomatic/malar volume augmentation. Learn more on the page Dermal Fillers with hyaluronic acid


Radiofrequency is one of the most effective non-invasive methods for visibly firming and toning the skin. Radiofrequency energy stimulates the contraction of existing collagen fibers and the production of new cells to smooth, tone, and firm the skin. Learn more on the radiofrequency page


Micro-needling is done through a natural stimulation based on micro-needles that penetrate the dermis favoring the formation of new collagen fibers, which give firmness and support to the skin. Learn more on the Microneedling page

Are Dermal Filler and Anti-Wrinkle injection the same thing?

No, the treatments have different characteristics:

  • Injeção Anti-Rugas: indicado para o tratamento de rugas estáticas ou dinâmicas, com o objetivo de diminuir e prevenir a formação de rugas e linhas de expressão e focado na área muscular;
  • Dermal filler with hyaluronic acid: used to fill in places where the skin lacks volume, such as deeper creases.
Is it possible to receive both Dermal Fillers and Anti-Wrinkle Injections on the same day?

Yes, it is possible to do both treatments on the same day. It is, in fact, through the combination of these two types of facial treatments that the best results are obtained.

Other treatments for Facial Rejuvenation

Learn more about each of them!

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